Updated

George Clooney had an epic blowup over President Obama with Steve Wynn in Las Vegas that ended with the actor calling Wynn “an a - - hole” and storming off as the casino mogul’s security guards got ready to pounce on him.

Clooney came to verbal blows with the famously tough Wynn while dining at his Encore hotel with Rande Gerber.

A source told Page Six, “George and Rande were in Vegas for a party for their Casamigos tequila and had an early dinner with Wynn and other associates.

“Things turned nasty as Wynn was provoking George, talking about politics. At first George just wasn’t responding. He just sat there politely listening,” the source said. But “Steve kept pushing and pushing, then started raising his voice. George still didn’t respond, he really didn’t want to get into it.”

But finally, Wynn figured out how to push the “Gravity” star’s buttons. “Discussing Obamacare, Steve called Obama ‘an a - - hole,’” said our source. “George responded, ‘President Obama is my friend, don’t talk about him like that.’ Wynn then shot back, ‘Your friend is an a - - hole!’

“George glared at Steve and said, ‘No! You are an a - - hole, and I’m not going to sit here any more and listen to this!’”

Reps for Clooney and Wynn didn’t comment. But Wynn had claimed Clooney was downing tequila shots and told the Las Vegas Review Journal of the dust-up with the star two weeks ago, “When he’s drinking, he considers himself a close personal buddy of the president.”

Wynn added “Clooney’s fun to be with when he’s sober. If you have a chance to drink with him, you want to get there early, and don’t stay late.”

Go to Page Six for more.