The clash started when Blair allegedly complained to "Anger Management" executives about Sheen's unprofessionalism and called him a "menace" to work with. Sheen found out about Blair's comments and, according to the report, said he fired Blair himself.
He also told the show's crew that he would refuse to shoot if she showed up on the set Monday, according to TMZ.
Sheen reportedly already has his eye on a replacement for Blair: Mila Kunis (who happens to be dating Ashton Kutcher, who replaced Sheen after he was fired from Two and a Half Men). Sheen has extended an offer to Kunis to guest-star on Anger Management for 10 episodes, at a rate of $1 million per episode, TMZ reports.
E-mails to FX, as well as Blair's and Sheen's reps, were not immediately returned.