The sitcom star, 73, will have a meningioma, or a benign tumor of the linking tissue of her brain, removed.
"At the recommendation of her neurologist, who has been monitoring this for years, and a neurosurgeon, Mary decided to proceed with this fairly routine procedure," her rep told the magazine.
The former “Dick Van Dyke Show” and “Mary Tyler Moore” show star did not reveal when she will go in for the procedure.
The actress was in good spirits last week, when she taped “The Rachael Ray Show.” The episode, which aired Thursday, was dedicated to the "Dick Van Dyke" show.
Moore recently appeared with her friend and former “Mary Tyler Moore Show” costar Betty White on White’s sitcom “Hot in Cleveland.”