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George Lopez extended an olive branch to Kirstie Alley Friday when he invited her to be  a guest on his show after she rejected his apology via Twitter for comparing her to a pig Wednesday.

In an interview with “Access Hollywood,” Lopez said his joke was “poor judgment. As they say in my world of golf, ‘bad form on my part.’”

“I’ve apologized. I think she’s accepted my apology, I wish that she had and that she would be a guest on ‘Lopez Tonight,’” the comedian said. “ I would love to have her on.”

“Listen, she has a lot of fans and when you make a joke of that type, um, it never goes over well.”

But contrary to what he thought, Alley did not accept his apology, and instead demanded one of his kidneys.

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“I don’t need or want ur apology…I want your kidney dude .. on behalf of ur X and all the women uv insulted…give it back,” she said referring to Lopez’s ex-wife Ana giving him one of her kidneys in 2005.

She added, “ I don’t consider ‘I misjudged the joke’ an apology. sorta like a husband saying ‘I misjudged putting my d**k in a whore…sorry hon..hehe.”

Lopez’s original apology, which he Tweeted, read, ““I misjudged the joke.  No malice was intended and I apologize to Kirstie.”

Many were not amused by Lopez’s callous “joke,” considering that 60-year-old Alley has struggled very publicly with weight issues over the years, at one point tipping the scales at 230 pounds and sparking speculation she suffers with a compulsive eating disorder.

Rather than apologizing on air during his show, Lopez opted for Twitter, using 60 characters of the 140 characters allotted. During his monologue last night, Lopez didn’t even mention Alley, but took a few minutes to make fun of Shaquille O’Neill’s weight (joking that he couldn’t be pulled away from the Wendy’s drive-through) and Kim Kardashian’s as well (joking that W magazine ran out of ink when trying to cover her assets on her nude cover).

TBS declined to comment on Lopez’s remarks.

Experts slammed Lopez’s comments to FOX411's Pop Tarts column on Thursday. "Lopez's comments were not only demeaning to Alley, who has been incredibly brave and open with her journey toward health, but they were very detrimental to women and girls everywhere," said Yana Walton, Vice President of Communications for watchdog group the Women’s Media Center. "In a country where eating disorders are an epidemic, where advertising continually implies women are deeply deficient, where media places the majority of women's worth on their appearances, this is unacceptable."

“Lopez should use his creativity to make jokes that aren’t this harmful," Walton said. "And Alley should be judged on her dancing. After all, this is a show about dance - it's not 'The Biggest Loser.’”

Terri Dougherty, editor of Women Magazine, feels some in Hollywood need to shape up and actually produce some original, funny material.

“Lopez made a cheap shot that simply was not very funny. Dancing is excellent exercise and I'm happy to see Kirstie out there. Making fun of a person's looks may be a standard part of comedians' acts, but this certainly was not a fresh or humorous take,” she said.

Author of “Love Your Body, Love Your Life” Sarah Maria said Lopez’s snide jab at Alley is offensive to all women.

“Lopez’s attempt at comedy is cruel, demeaning, and insulting.  In an apparent attempt to make people laugh, Lopez chooses insults over intelligence,” she said. “Did Lopez even graduate from pre-school?  Even without considering Alley’s personal ongoing weight struggle, such a cruel comment is an insult to women and men everywhere. One hopes that after pre-school, maybe at the very latest grade school, children outgrow such hurtful and inane comments.”

But it isn’t only male comedians making disparaging weight-related remarks. Just a few months ago, comedian Kathy Griffin launched a “fat” attack against last season’s “Dancing With the Stars” contestant Bristol Palin, likening her to the 350-pound fictional character “Precious.”

FoxNews.com's Hollie McKay contributed to this report.