According to Us Magazine, the pair split amicably after the relationship had "simply run its course," and the two plan to remain friends.
Could this leave an opening for Fox's co-star Shia LaBeouf to run through?
The Transformers stars, who just wrapped up filming the sequel to their mega-hit, have expressed their admiration for one another in the past.
Fox, 22, said in 2007 that “Shia is the best kisser ever,” and gushed about their on-screen romance.
In the August 2007 issue of Vanity Fair magazine, LaBeouf, also 22, admitted that it is “really easy to fall for someone on set.”
And in September, the stars walked the red carpet at LaBeouf’s film premiere Eagle Eye, raising eyebrows yet again as they smiled and embraced for photographers.