The star of "The Beast" is talking to publishers about the project next week.
Swayze's wife Lisa will co-write the book, Swayze's rep confirms to Us Magazine.
The actor has been battling pancreatic cancer since it was diagnosed in 2008.
"There's a lot of fear here," Swayze, 56, told Barbara Walters in a television interview. "There's a lot of stuff going on. Yeah, I'm scared. Yeah, I'm angry. Yeah, I'm [asking] why me. Yeah, I'm all this stuff. You can bet that I'm going through hell. And I've only seen the beginning of it."
Swayze told Walters he has been dealing with issues of mortality as well.
"I don't know what's on the other side. It tests everything I believe in … that here is something unique in all of us that does not, does not die."